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Version 1.0 | Update 9Jul11
Edited by
Paul Quin
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Premature Physical Aging
in People Living with Hiv


“Functional Impairment associated with low bone and muscle mass among persons aging with HIV­ infection”, recently published in the Journal of Acquired Immune Deficiency Syndromes, suggests that factors associated with physical frailty in elderly populations are now being seen in middle-­aged HIV-positive individuals.

Research by investigators at the University of Colorado Hospital hoped to uncover the relationship between premature development of classic characteristics of old age – such as decreased muscle mass and low mineral bone density – and HIV infection.

Researchers concluded that decreased functional capacity in middle-­aged people living with HIV may be associated with these signs of premature aging, leaving this population vulnerable to diseases of old age and other complications, including increased risk for fractures and decreased ambulatory function.

In establishing this connection, researchers have opened the door to further investigation regarding interventions for preventing these premature changes, thereby increasing longevity and quality of life in people living with HIV.

More information on AIDSmap.

Reference: Erlandson, KM, et al. Functional impairment is associated with low bone and muscle mass among persons aging with HIV infection. J Acquir immune Defic Syndr, online edition. DOI: 10.1097/QAI.0b013e318289bb7e, 2013